03.1 Environment
ENVIRONMENT
LAND
Nearly 40% of all land is used for agriculture. 52% of this land has already degraded, threatening food security worldwide. However, faced with long-term declines in productivity and water scarcity, farmers paradoxically resort to even more aggressive use of harmful agrochemicals and inefficient irrigation systems, only exacerbating the crisis (UNCCD, 2022). Every year, we lose another 100 million hectares of healthy and productive land (UNCCD Data Dashboard, 2024). The number of pesticide applications has doubled over the last 25 years (Goulson et al., 2018). At the same time, the impact of pesticides (applied en masse and often legally) on cancer incidence can rival the harm from smoking (Deep Science Ventures, 2025). Toxicity has permeated everywhere — an analysis of honey samples from around the world showed that 75% of them contain neonicotinoid insecticides (Mitchell et al., Science, 2017).
AIR
More than 90% of the world's population is exposed to air pollution at levels above WHO guidelines (Deep Science Ventures, 2025). This is the cause of one in eight deaths on the planet, making air pollution the second most significant risk factor for death in the world (State of Global Air, 2024). It is particularly telling that those responsible for the sources of this pollution or for their regulation breathe this same air. Our analysis will mention other similar paradoxes that raise serious doubts about the rationality of the actors involved.
WATER AND "FOREVER CHEMICALS"
PFAS have polluted the entire world; in many places, concentrations in rainwater are so high that it cannot be considered safe for drinking (Deep Science Ventures, 2025). At least one type of PFAS is found in 45% of tap water samples in the US (USGS, 2023). PFAS are found in the blood of almost all US residents (CDC/NHANES, 2024).
More than half of rivers and almost all coastal marine waters in Europe (bays, estuaries) exceed safety standards for "forever chemicals." In some countries (France, Belgium), 100% of tested water bodies were found to be contaminated (JRC, 2024). In the US, PFAS are found in freshwater fish in all 48 contiguous states; out of 349 samples, only 1 was without detectable PFAS, and in a separate sample, 152 out of 152 samples had detectable PFAS (100%) (N. Barbo et al., 2023). PFAS have penetrated even the oceans — they are found in all layers of the marine food chain: from coastal dolphins to deep-sea predators. Even the most remote whales contain high concentrations of PFAS (Pereira et al., 2025). This means that both humans and animals are exposed to their influence and associated risks.
PFAS are associated with increased metabolic and cardiovascular risks. PFAS in drinking water are linked to higher incidence rates of several cancer groups (digestive, endocrine, oral/pharyngeal, respiratory) (Nature, 2025), and increased PFAS in blood is linked to a higher probability of type 2 diabetes (~+31%) (eBioMedicine, 2025) and worsening cardiovascular health (~+62%) (Frontiers in Public Health, 2024); meta-analyses also show measurable shifts in thyroid hormones (Science of the Total Environment, 2024).
"Forever chemicals" do not decompose. They accumulate in the environment and in the body. At the same time, there is no safe threshold below which there would be no harm to health. Even low levels, common among the general population, already show a negative correlation [Exposure and Health, 2024]. When consuming just one serving of local freshwater fish per year, the level of PFOS (one of the PFAS) in the blood can increase noticeably; according to the authors' estimate, one serving per year is comparable to about a month of drinking water with high PFOS content (Environmental Research, 2023).
This is not a surprise. PFAS have long been known for their negative effects; once some of them were banned, corporations switched to others.
PLASTIC
The chemical basis of the modern plastic industry: phthalates (make plastic flexible and elastic, e.g., PVC, food films, toys, IV drips), bisphenols (make plastic hard and transparent, e.g., office water bottles), flame retardants (fire-protective additives in household appliances, furniture, cars), and others. They are used everywhere due to their low cost and convenience. The cumulative mortality from just these three groups is about 600,000 people per year in the 38 countries studied (The Lancet, 2025). With direct extrapolation to the world, the figure could be about 2 million deaths annually, which exceeds the number of deaths in traffic accidents.
Microplastics and nanoplastics: discovered almost everywhere, including in human brain tissue, where their concentration has increased by approximately 50% over the last 8 years (University of New Mexico, 2025). Polyethylene microplastics can act as a "Trojan horse," facilitating the entry of BPA into cells; the combined exposure to PE-microplastics and BPA causes synergistic toxic effects and endocrine disruption (Scientific Reports, 2025). In addition to their own additives, microplastics exhibit a "vector effect": they adsorb hydrophobic organic pollutants from water, transport them, and release them in the intestines of aquatic organisms, which leads to increased bioaccumulation (Chemosphere, 2025).
Lack of information: This is the proven minimum damage from the three most studied groups of chemicals — three out of many others. At the same time: "Approximately 75% of chemicals contained in plastic have not been assessed for their impact on human health. Of those for which data are available, approximately 75% were identified as particularly hazardous due to their toxicity, persistence, bioaccumulation potential, and mobility. Almost 1,500 of these chemicals are carcinogenic, mutagenic, or toxic to the reproductive system, and more than 1,700 are toxic to specific organs, such as the liver. 47 of these chemicals are recognized in the EU as endocrine disruptors, and for more than 1,800, it has been shown that they leach from plastic and have high potential for human exposure. At the same time, with the exception of these chemicals, for the majority of plastic products we encounter in everyday life, little or no information is available regarding their chemical composition, toxic effects, or potential danger. The lack of transparency regarding which chemicals are present in plastic, their applications, production volumes, and toxic effects limits our understanding of the full spectrum of potential harm from chemicals in plastic to human health and the planet" (The Lancet Countdown on health and plastics, 2025).
Despite this, water continues to be sold all over the world in plastic bottles and office jugs, and even storage and transportation methods do not take into account factors that exacerbate the leaching of chemicals into water (e.g., heating, solar radiation, or aging of the packaging). At the same time, testing for the presence of PFAS and purification from them is also an extremely rare practice.
This means that the majority of the population of the US and Europe, and likely the entire planet, regularly consumes water exposed to both factors simultaneously — both contamination by toxic plastic leachates and PFAS.
REGULATORS
"The world is struggling with rising cancer incidence, declining fertility, and an increase in chronic diseases... The industrial economy has created more than 100 million new chemical substances... Our understanding of toxicity is outdated because it relies on the 500-year-old concept that 'the dose makes the poison.' Regulators and corporations still rely primarily on an outdated toxicological model that ignores non-monotonic dose-response curves, the combined effect of multiple chemicals, and differences between sexes. This model uses high doses to estimate safe thresholds and therefore often overlooks the toxic effects of low doses, especially in the case of endocrine disruptors" (Deep Science Ventures, 2025, my translation).